Contains acetaminophen. For the temporary relief of minor arthritis pain. Lasts up to 8 hours. Patented time release caplets. Capsule-shaped tablets. Ease-of-Use commendation for packaging - Arthritis foundation. Contains no aspirin. What makes Tylenol Arthritis Pain Extended Relief Caplets different? Uses a unique, patented bi-layer caplet. The first layer dissolves quickly to provide prompt relief while the second layer is time released to provide up to 8 hours of relief.