Acetaminophen, chlorpheniramine maleate (antihistamine in nighttime dose only), dextromethorphan HBr, phenylephrine HCl. Pain reliever/fever reducer, antihistamine (antihistamine in nighttime dose only), cough suppressant, nasal decongestant. Daytime: nasal congestion, sore throat pain, headache, coughing; 12 coated caplets. Nighttime: relieves the same symptoms as daytime & more (Antihistamine in nighttime dose only) so you can sleep; 12 coated caplets.